Effect of Glycine on Extracellular Production of Glutamate Oxaloacetate Transaminase and Glutamate Pyruvate Transaminase

Effects of Vitamin B6 on the Brain Glutamate Pyrovate Transaminase and Glutamate Oxaloacetate Transaminase in Young and Old Rats

Excessive amounts of extracellular glutamate in brain are excitotoxic and lead to neuronal death. Glutamate pyrovate transamiase (GPT) and glutamate oxaloacetate transaminase (GOT) catalyze transamination of glutamate to alpha ketoglutarate. Because vitamin B6 is essential for the enzymes activities, this study was undertaken to examine the effect of vitamin B6 on age related changes of this en...

Role of Glutamate-oxaloacetate Transaminase and Malate Dehydrogenase in the Regeneration of NAD for Glycine Oxidation by Spinach leaf Mitochondria.

During glycine oxidation by spinach leaf mitochondria, oxygen consumption showed a strong and transient inhibition upon addition of oxaloacetate or aspartate plus alpha-ketoglutarate. During the course of the inhibition, aspartate and alpha-ketoglutarate were stoichiometrically transformed into malate and glutamate.It is concluded that oxaloacetate formed by transamination is reduced by the mal...

The intracellular distribution, latency and electrophoretic mobility of L-glutamate-oxaloacetate transaminase from rat liver.

Richardson, E. M., Bulaschenko, H. & Dohan, F. C. (1958). J. clin. Endocrin. 18, 666. Richardson, E. M., Touchstone, J. C., Dohan, F. C., Bulaschenko, H., Landolt, I. & Applin, W. (1955). J. clin. Invest. 34, 285. Rimini, E. (1901). Gazz. chim. ital. 31, II, 84. Romani, J. D. (1956a). C.R. Soc. Biol., Paris, 150, 644. Romani, J. D. (1956b). C.R. Soc. Biol., Paris, 150, 887. Romani, J. D. & Able...

Interaction between beta-fluoro-oxaloacetate and glutamate-aspartate transaminase of heart mitochondria.

Determination of the Chromosomal Location of a Glutamate Oxaloacetate Transaminase Structural Gene Using Triticum-agropyron Translocations1

The glutamate oxaloacetate transaminase (GOT) zymogram phenotypes of a series of 15 translocation lines, a chromosome addition line and a chromosome substitution line were determined. In each of the translocation lines a segment of the long arm of Triticum aestivum chromosome 3D has been replaced by a portion of an Agropyron elongatum homoeologue. Evidence was obtained that the products of the ...